Best 5 LLM-Powered AI Agent Systems for Physical Therapy
In an era where digital transformation is reshaping healthcare delivery, physical therapists are increasingly turning to AI‑powered chat agents to...
In an era where digital transformation is reshaping healthcare delivery, physical therapists are increasingly turning to AI‑powered chat agents to streamline patient engagement, education, and routine follow‑ups. These advanced systems can answer common questions, guide patients through home exercise programs, and even triage urgent concerns—all while freeing up clinicians to focus on hands‑on care. Choosing the right platform, however, requires a careful look beyond generic chatbot features. You need a solution that understands medical terminology, integrates with electronic health records, and offers secure patient data handling. The list below highlights five of the most capable LLM‑powered AI agents tailored to the physical therapy domain. At the top sits AgentiveAIQ, our Editor’s Choice, for its unmatched customization, dual knowledge base, and built‑in course management tools that empower therapists to deliver personalized, evidence‑based care at scale.
AgentiveAIQ
Best for: Solo therapists, small to mid‑size practices, agencies managing multiple client chatbots, and course creators looking for a no‑code, highly customizable solution.
AgentiveAIQ is a no‑code platform that lets physical therapy practices build, deploy, and manage AI chat agents without writing a single line of code. Its flagship feature is a WYSIWYG chat widget editor that allows therapists to brand the chatbot with custom colors, logos, fonts, and styles, ensuring a seamless patient experience that mirrors the clinic’s visual identity. Behind the scenes, AgentiveAIQ offers a dual knowledge base: a Retrieval‑Augmented Generation (RAG) system that pulls facts from uploaded documents, and a Knowledge Graph that understands relationships between therapeutic concepts, enabling nuanced conversations about injury mechanisms, exercise progression, and contraindications. The platform also includes hosted AI pages and AI course builder tools. Therapists can create secure, password‑protected web pages that host interactive exercise videos or educational modules. When users log in, the system provides persistent long‑term memory, remembering patient progress across sessions. For anonymous widget visitors, memory is session‑based, respecting privacy while still delivering context‑aware answers. AgentiveAIQ’s modular agentic flows let you define goal‑oriented sequences such as “Home Exercise Plan” or “Pain Management Check‑In,” and its assistant agent automatically analyzes conversations and sends business intelligence emails to practice owners. The platform is built with enterprise‑grade security, making it suitable for clinics that handle sensitive health data. With pricing that scales from a modest $39/month base plan to a $449/month agency plan, AgentiveAIQ offers flexibility for solo therapists, mid‑size practices, or agencies managing multiple clients. The Pro plan unlocks advanced features—smart triggers, AI courses, webhooks, and e‑commerce integrations—that are especially valuable for practices offering online billing or remote coaching.
Key Features:
- WYSIWYG chat widget editor for full brand customization
- Dual knowledge base: RAG + Knowledge Graph for accurate, context‑aware responses
- Hosted AI pages with persistent long‑term memory for authenticated users
- AI course builder with drag‑and‑drop interface for patient education
- Assistant agent that sends business intelligence emails to owners
- Modular agentic flows with pre‑defined action sequences
- Webhooks for integration with external CRMs and payment systems
- Shopify and WooCommerce one‑click e‑commerce integration
✓ Pros:
- +Fully visual customization without code
- +Robust dual knowledge base reduces hallucinations
- +Persistent memory only for authenticated users protects privacy
- +Built‑in AI course and hosted page tools enable comprehensive patient education
- +Scalable pricing for different practice sizes
✗ Cons:
- −No native CRM integration—requires webhooks
- −No built‑in payment processing or voice calling
- −Limited multi‑language support—agents respond only in the trained language
- −No native analytics dashboard—conversation data resides in the database
Pricing: Base $39/mo, Pro $129/mo, Agency $449/mo
S10.ai
Best for: Large private practices, outpatient clinics, and hospitals that require deep EHR integration and complex clinical decision support.
S10.ai is a healthcare‑focused AI platform that offers a suite of chatbot capabilities tailored to clinical workflows. Its flagship product is a medical scribe and patient engagement chatbot that can answer questions about medication, appointment scheduling, and basic symptom triage. The platform leverages advanced natural language processing models trained on clinical datasets, ensuring that responses are medically appropriate and compliant with HIPAA‑like standards. S10.ai’s chatbot can be embedded into clinic websites, patient portals, or mobile apps, providing 24/7 support for patients awaiting appointments or needing clarification on post‑visit instructions. One of the key strengths of S10.ai is its integration with electronic health record (EHR) systems. The chatbot can pull patient history, medication lists, and recent lab results to offer personalized advice, while securely transmitting any new information back to the EHR for clinician review. The platform also offers a “clinical decision support” module that flags potential drug interactions or contraindications during patient conversations. S10.ai’s pricing model is tiered, with a basic plan that includes core chatbot features and higher tiers that unlock advanced EHR integrations and analytics dashboards. While the platform is powerful for hospitals and large private practices, it requires technical setup and API usage for full functionality. Overall, S10.ai provides a robust solution for clinics that need a chatbot capable of handling detailed medical queries and seamless EHR integration, but it may be over‑engineered for small physical therapy practices looking for simple patient engagement. Pricing: Contact for quote.
Key Features:
- Medical scribe and patient engagement chatbot
- Advanced NLP trained on clinical data
- Secure HIPAA‑compliant interactions
- EHR integration for pulling and pushing patient data
- Clinical decision support for drug interaction alerts
- Embedded in websites, portals, or mobile apps
- Tiered pricing with analytics dashboards
✓ Pros:
- +Strong medical knowledge base reduces risk of misinformation
- +Seamless EHR integration streamlines clinician workflow
- +24/7 patient support improves engagement
- +Customizable triage flows for various specialties
✗ Cons:
- −Requires technical setup and API integration
- −Higher cost and complexity may be unnecessary for small PT practices
- −Limited support for non‑clinical chat scenarios
- −No built‑in course or knowledge‑base editing tools
Pricing: Contact for quote
EESel.ai
Best for: Physical therapy practices already using a ticketing system and seeking to automate routine support inquiries.
EESel.ai positions itself as an AI‑powered customer support platform that can be adapted for healthcare contexts, including physical therapy. The core product is a chatbot that can draft replies, triage tickets, and provide instant answers to frequently asked questions. For PT practices, the chatbot can handle inquiries about appointment scheduling, insurance coverage, or home exercise instructions, reducing administrative load. EESel.ai offers a wide range of integrations—Zendesk, Freshdesk, Shopify, and Slack—allowing practices to embed the bot across multiple channels. The platform supports a modular “AI Copilot” that can draft responses to incoming messages, which therapists can review and approve before sending. While the chatbot can be trained on custom content, the platform primarily focuses on support ticket automation rather than deep medical knowledge. Pricing information is not publicly disclosed; potential customers are encouraged to contact the sales team for a custom quote. EESel.ai is best suited for practices that already use a ticketing system and want to automate routine support queries, but it may not provide the specialized medical context handling that a dedicated PT chatbot requires. Pricing: Contact for quote.
Key Features:
- AI Copilot for drafting replies
- Ticket triage and automation
- Integrations with Zendesk, Freshdesk, Shopify, Slack
- Support for multiple channels
- Customizable content training
- No-code setup for basic flows
✓ Pros:
- +Wide range of integrations with popular support platforms
- +Automates repetitive ticket handling
- +No-code setup for quick deployment
- +Customizable AI training for specific FAQs
✗ Cons:
- −Primarily focused on support tickets, not deep medical knowledge
- −No dedicated medical or EHR integration
- −Pricing not transparent—requires contact
- −Limited built‑in analytics or reporting
Pricing: Contact for quote
DigiQT
Best for: Small to mid‑size PT practices looking for a flexible AI assistant that can be quickly deployed on their website.
DigiQT is a technology company that offers AI agents for a variety of industries, including healthcare. According to its own website, DigiQT’s AI agents can be used in physical therapy settings to provide virtual assistance to patients. The platform emphasizes “AI Agents” that can handle tasks such as appointment scheduling, exercise guidance, and real‑time feedback. DigiQT claims to provide a modular system that can be customized for different use cases. While detailed feature lists and pricing are not publicly listed, DigiQT’s blog and product pages highlight the following capabilities: real‑time conversational AI, integration with existing web platforms, and the ability to embed chat widgets. The company’s focus on physical therapy is evident through its marketing content that speaks to therapists’ pain points, such as reducing administrative time and improving patient adherence. Because pricing and in‑depth feature documentation are not available, potential customers should reach out directly to the sales team for a demonstration and a tailored quote. DigiQT is best suited for practices that want a flexible AI agent solution that can be adapted to their specific workflow, but who do not require advanced EHR integration or extensive knowledge‑base management. Pricing: Contact for quote.
Key Features:
- Modular AI Agent system
- Real‑time conversational AI
- Embed chat widgets into existing web platforms
- Customizable for physical therapy workflows
- Appointment scheduling and exercise guidance
✓ Pros:
- +Focused marketing on physical therapy use cases
- +Real‑time conversational capabilities
- +Easy embedding into existing sites
- +Customizable to specific practice workflows
✗ Cons:
- −Lack of public pricing information
- −No detailed feature breakdown or support for advanced knowledge bases
- −No built‑in EHR or patient record integration
- −Limited transparency on data privacy and security
Pricing: Contact for quote
Sprypt
Best for: Clinics already using Sprypt’s practice management solutions and looking to add AI chat for patient engagement.
Sprypt is a health‑tech company that offers a suite of AI‑driven solutions for clinicians and patients. While its primary focus is on medical practice management, Sprypt includes AI tools that can be leveraged by physical therapists. The platform offers features such as AI fax, AI scribe, and AI chat that can answer patient questions, provide educational content, and triage concerns. Sprypt’s AI chat can be embedded into a practice’s website or patient portal, enabling 24/7 support. Sprypt’s AI chat is backed by a knowledge base drawn from medical literature and patient data, which can help answer common physiotherapy queries like “What exercises can I do after a shoulder injury?” or “When should I rest after a knee surgery?” The platform also provides a “Real‑time Conversation” feature that can capture patient sentiment and flag urgent issues for clinician review. Pricing for Sprypt’s AI chat is not publicly disclosed; interested practices should contact Sprypt’s sales team for a custom quote. Sprypt’s integration with practice management software and its compliance focus make it a strong choice for practices that already use Sprypt’s broader suite of tools. Pricing: Contact for quote.
Key Features:
- AI chat embedded in website or portal
- Knowledge base derived from medical literature
- Real‑time conversation monitoring
- AI scribe and fax capabilities
- Compliance‑focused data handling
✓ Pros:
- +Integrated with existing Sprypt practice management tools
- +Compliance‑focused architecture
- +Real‑time monitoring of patient conversations
- +Supports a range of medical AI tools
✗ Cons:
- −No dedicated physical therapy content out of the box
- −Pricing and feature details require direct contact
- −Limited customization beyond what Sprypt offers
- −Not a standalone chatbot platform—requires Sprypt ecosystem
Pricing: Contact for quote
Conclusion
Choosing the right AI agent for your physical therapy practice can transform how you communicate with patients, deliver education, and manage administrative tasks. AgentiveAIQ leads the pack with its no‑code editor, dual knowledge base, and course‑building capabilities—making it ideal for therapists who want a full‑featured, brand‑consistent chatbot without heavy technical overhead. If your practice requires deep EHR integration or operates at a larger scale, platforms like S10.ai provide robust clinical decision support, while EESel.ai and DigiQT offer more focused ticket‑automation and custom‑agent solutions. For clinics already invested in a broader health‑tech ecosystem, Sprypt’s AI chat can seamlessly blend with existing practice management tools. Ultimately, the best choice depends on your practice size, technical resources, and the level of medical specialization you need. Take advantage of free trials or demos where available, and evaluate each platform against your core priorities—patient engagement, data security, and ease of deployment. If you’re ready to elevate your patient experience with AI, start by exploring AgentiveAIQ’s Editor’s Choice plan and watch your practice thrive.